The PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cells

Spontaneous preterm delivery is linked to intrauterine inflammation. Fetal membranes are involved in the inflammatory process as an important source of mediators, and the chorion leave produces high levels of the pro-inflammatory cytokine TNFα when stimulated by LPS. The transcription factor NF-κB i...

Full description

Saved in:
Bibliographic Details
Main Authors: Hervé, Roxane, Schmitz, Thomas, Evain-Brion, Danièle, Cabrol, Dominique, Leroy, Marie-Josèphe, Méhats, Céline
Format: Artigo
Language:Inglês
Published: American Association of Immunologists 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198604/
https://ncbi.nlm.nih.gov/pubmed/18641359
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items