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Warfarin Anticoagulation Exacerbates the Risk of Hemorrhagic Transformation after rt-PA Treatment in Experimental Stroke: Therapeutic Potential of PCC

BACKGROUND: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset. We investigated whether warfarin exacerbates the risk of thrombolysi...

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Detalhes bibliográficos
Main Authors: Pfeilschifter, Waltraud, Spitzer, Daniel, Pfeilschifter, Josef, Steinmetz, Helmuth, Foerch, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198453/
https://ncbi.nlm.nih.gov/pubmed/22039437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026087
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