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12/15-LOX inhibition or knockout reduces warfarin-associated hemorrhagic transformation following experimental stroke
BACKGROUND AND PURPOSE: For stroke prevention, patients with atrial fibrillation typically receive oral anticoagulation. The commonly used anticoagulant warfarin increases the risk of hemorrhagic transformation (HT) when a stroke occurs, however, and tissue plasminogen activator (tPA) treatment is r...
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| Publicado no: | Stroke |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5263178/ https://ncbi.nlm.nih.gov/pubmed/28057806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.014790 |
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