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Dual antiplatelet therapy increases hemorrhagic transformation following thrombolytic treatment in experimental stroke

BACKGROUND AND PURPOSE—: Dual antiplatelet treatment (DAPT) poses a risk for increased hemorrhagic transformation (HT) following intravenous thrombolysis and mechanical thrombectomy. The aim of this study was to implement a model of experimental stroke with tPA-associated HT in mice on DAPT to enabl...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Zheng, Yi, Lieschke, Franziska, Schaefer, Jan Hendrik, Wang, Xiaoying, Foerch, Christian, van Leyen, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878181/
https://ncbi.nlm.nih.gov/pubmed/31587659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.119.027359
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