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Molecular Basis of Bcl-X(L)-p53 Interaction: Insights from Molecular Dynamics Simulations
Bcl-X(L), an antiapoptotic Bcl-2 family protein, plays a central role in the regulation of the apoptotic pathway. Heterodimerization of the antiapoptotic Bcl-2 family proteins with the proapoptotic family members such as Bad, Bak, Bim and Bid is a crucial step in the apoptotic regulation. In additio...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198449/ https://ncbi.nlm.nih.gov/pubmed/22039431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026014 |
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