Dynamics of Bcl-xL in Water and Membrane: Molecular Simulations

The Bcl2 family of proteins is capable of switching the apoptotic machinery by directly controlling the release of apoptotic factors from the mitochondrial outer membrane. They have ‘pro’ and ‘anti’-apoptotic subgroups of proteins which antagonize each other’s function; however a detailed atomistic...

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Bibliographic Details
Main Authors: Maity, Atanu, Yadav, Seema, Verma, Chandra S., Ghosh Dastidar, Shubhra
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792877/
https://ncbi.nlm.nih.gov/pubmed/24116174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076837
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