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Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane

The anti-apoptotic Bcl-2 family protein Bcl-xL plays a critical role in cell survival by protecting the integrity of the mitochondrial outer membrane (MOM). The mechanism through which Bcl-xL is recruited to the MOM has not been fully discerned. The retromer is a conserved endosomal scaffold complex...

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書目詳細資料
發表在:Mol Biol Cell
Main Authors: Farmer, Trey, O’Neill, Katelyn L., Naslavsky, Naava, Luo, Xu, Caplan, Steve
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724524/
https://ncbi.nlm.nih.gov/pubmed/30840537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-01-0044
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