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Molecular Dynamic Simulation Insights into the Normal State and Restoration of p53 Function
As a tumor suppressor protein, p53 plays a crucial role in the cell cycle and in cancer prevention. Almost 50 percent of all human malignant tumors are closely related to a deletion or mutation in p53. The activity of p53 is inhibited by over-active celluar antagonists, especially by the over-expres...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Molecular Diversity Preservation International (MDPI)
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431824/ https://ncbi.nlm.nih.gov/pubmed/22949826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13089709 |
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