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Molecular Dynamic Simulation Insights into the Normal State and Restoration of p53 Function

As a tumor suppressor protein, p53 plays a crucial role in the cell cycle and in cancer prevention. Almost 50 percent of all human malignant tumors are closely related to a deletion or mutation in p53. The activity of p53 is inhibited by over-active celluar antagonists, especially by the over-expres...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fu, Ting, Min, Hanyi, Xu, Yong, Chen, Jianzhong, Li, Guohui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Molecular Diversity Preservation International (MDPI) 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431824/
https://ncbi.nlm.nih.gov/pubmed/22949826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13089709
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