Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

OBJECTIVE: Recently we have shown that calpain-1 activation contributes to cardiomyocyte apoptosis induced by hyperglycemia. This study was undertaken to investigate whether targeted disruption of calpain would reduce myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes. RESEARCH D...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Li, Ying, Ma, Jian, Zhu, Huaqing, Singh, Manpreet, Hill, David, Greer, Peter A., Arnold, J. Malcolm, Abel, E. Dale, Peng, Tianqing
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2011
Предметы:
Complications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198063/
https://ncbi.nlm.nih.gov/pubmed/21911754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1333
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы