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Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas
COL-3 is a chemically modified tetracycline that targets multiple aspects of matrix metalloproteinase regulation. This phase I clinical trial was conducted to determine the maximum tolerated dose (MTD) of COL-3 in adults with recurrent high-grade glioma, to describe the effects of enzyme-inducing an...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197967/ https://ncbi.nlm.nih.gov/pubmed/21547395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0602-9 |
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