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Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma,
Penicillamine is an oral agent used to treat intracerebral copper overload in Wilson’s disease. Copper is a known regulator of angiogenesis; copper reduction inhibits experimental glioma growth and invasiveness. This study examined the feasibility, safety, and efficacy of creating a copper deficienc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Duke University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1871917/ https://ncbi.nlm.nih.gov/pubmed/16053699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704000869 |
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