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The Aneuploidy Paradox: Costs and Benefits of an Incorrect Karyotype

Aneuploidy has a paradoxical effect on cell proliferation. In all normal cells analyzed to date, aneuploidy has been found to decrease the rate of cell proliferation. Yet, aneuploidy is also a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequently recove...

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Autors principals: Sheltzer, Jason M., Amon, Angelika
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197822/
https://ncbi.nlm.nih.gov/pubmed/21872963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2011.07.003
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