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The Aneuploidy Paradox: Costs and Benefits of an Incorrect Karyotype
Aneuploidy has a paradoxical effect on cell proliferation. In all normal cells analyzed to date, aneuploidy has been found to decrease the rate of cell proliferation. Yet, aneuploidy is also a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequently recove...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197822/ https://ncbi.nlm.nih.gov/pubmed/21872963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2011.07.003 |
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