Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury

We investigated whether plasma long-chain sphingoid base (LCSB) concentrations are altered by transient cardiac ischemia during percutaneous coronary intervention (PCI) in humans and examined the signaling through the sphingosine-1-phosphate (S1P) cascade as a mechanism underlying the S1P cardioprot...

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Detalhes bibliográficos
Main Authors: Egom, Emmanuel Eroume A., Mohamed, Tamer M. A., Mamas, Mamas A., Shi, Ying, Liu, Wei, Chirico, Debora, Stringer, Sally E., Ke, Yunbo, Shaheen, Mohamed, Wang, Tao, Chacko, Sanoj, Wang, Xin, Solaro, R. John, Fath-Ordoubadi, Farzin, Cartwright, Elizabeth J., Lei, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Signaling and Stress Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197364/
https://ncbi.nlm.nih.gov/pubmed/21705677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01003.2010
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