Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic mice

Accumulation of cholesteryl ester (CE)-enriched macrophage foam cells is central to the development of atherosclerotic lesions. Intracellular CE hydrolysis is the rate-limiting step in the removal of free cholesterol from macrophage foam cells. Enhancing this process by transgenic overexpression of...

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Main Authors: Bie, Jinghua, Zhao, Bin, Ghosh, Shobha
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197345/
https://ncbi.nlm.nih.gov/pubmed/21795638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00277.2011
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