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Modular Strategy for the Construction of Radiometalated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels–Alder Click Chemistry
[Image: see text] A modular system for the construction of radiometalated antibodies was developed based on the bioorthogonal cycloaddition reaction between 3-(4-benzylamino)-1,2,4,5-tetrazine and the strained dienophile norbornene. The well-characterized, HER2-specific antibody trastuzumab and the...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2011
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197258/ https://ncbi.nlm.nih.gov/pubmed/21877749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200288d |
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