Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

Parkinson's disease (PD) is histologically well defined by its characteristic degeneration of dopaminergic neurons in the substantia nigra pars compacta. Remarkably, divergent PD-related mutations can generate comparable brain region specific pathologies. This indicates that some intrinsic regi...

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Hlavní autoři: Diedrich, Madeleine, Kitada, Tohru, Nebrich, Grit, Koppelstaetter, Andrea, Shen, Jie, Zabel, Claus, Klose, Joachim, Mao, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196908/
https://ncbi.nlm.nih.gov/pubmed/21943346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-9-59
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