Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

Parkinson's disease (PD) is histologically well defined by its characteristic degeneration of dopaminergic neurons in the substantia nigra pars compacta. Remarkably, divergent PD-related mutations can generate comparable brain region specific pathologies. This indicates that some intrinsic regi...

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Detalhes bibliográficos
Main Authors: Diedrich, Madeleine, Kitada, Tohru, Nebrich, Grit, Koppelstaetter, Andrea, Shen, Jie, Zabel, Claus, Klose, Joachim, Mao, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196908/
https://ncbi.nlm.nih.gov/pubmed/21943346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-9-59
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