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DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter

Despite the fact that 45% of all human gene promoters do not contain CpG islands, the role of DNA methylation in control of non-CpG island promoters is controversial and its relevance in normal and pathological processes is poorly understood. Among the few studies which investigate the correlation b...

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Bibliografiske detaljer
Main Authors: Han, Han, Cortez, Connie C., Yang, Xiaojing, Nichols, Peter W., Jones, Peter A., Liang, Gangning
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196883/
https://ncbi.nlm.nih.gov/pubmed/21835883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr356
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