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CpG islands: algorithms and applications in methylation studies
Methylation occurs frequently at 5′-cytosine of the CpG dinucleotides in vertebrate genomes; however, this epigenetic feature is rarely observed in CpG islands (CGIs) or CpG clusters in the promoter regions of genes. Aberrant methylation of the promoter-associated CGIs might influence gene expressio...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679166/ https://ncbi.nlm.nih.gov/pubmed/19302978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.076 |
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