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CpG islands: algorithms and applications in methylation studies

Methylation occurs frequently at 5′-cytosine of the CpG dinucleotides in vertebrate genomes; however, this epigenetic feature is rarely observed in CpG islands (CGIs) or CpG clusters in the promoter regions of genes. Aberrant methylation of the promoter-associated CGIs might influence gene expressio...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Zhongming, Han, Leng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679166/
https://ncbi.nlm.nih.gov/pubmed/19302978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.076
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