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Copper(II) enhances membrane-bound α-synuclein helix formation

Interactions of copper and membranes with α-synuclein have been implicated in pathogenic mechanisms of Parkinson’s disease, yet work examining both concurrently is scarce. We have examined the effect of copper(II) on protein/vesicle binding and found that both the copper(II) affinity and α-helical c...

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Detalhes bibliográficos
Main Authors: Lucas, Heather R., Lee, Jennifer C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196632/
https://ncbi.nlm.nih.gov/pubmed/21290070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mt00088d
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