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Copper Coordination to the Membrane Bound Form of α-Synuclein

Aggregation of the 140 amino acid protein α-synuclein (α-syn) is linked to the development of Parkinson’s disease (PD). α-Syn is a copper binding protein with potential function as a regulator of metal dependent redox activity. Epidemiological studies suggest that human exposure to excess copper inc...

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Detalhes bibliográficos
Main Authors: Dudzik, Christopher G., Walter, Eric D., Abrams, Benjamin S., Jurica, Melissa S., Millhauser, Glenn L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544399/
https://ncbi.nlm.nih.gov/pubmed/23252394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301475q
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