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Coodination Features and Affinity of the Cu(2+) Site in the α-Synuclein Protein of Parkinson’s Disease
Parkinson’s disease (PD) is the second most prevalent age-related, neurodegenerative disorder, affecting >1% of the population over the age of 60. PD pathology is marked by intracellular inclusions composed primarily of the protein α-synuclein (α-syn). These inclusions also contain copper and the...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064431/ https://ncbi.nlm.nih.gov/pubmed/21319811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101912q |
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