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Coodination Features and Affinity of the Cu(2+) Site in the α-Synuclein Protein of Parkinson’s Disease

Parkinson’s disease (PD) is the second most prevalent age-related, neurodegenerative disorder, affecting >1% of the population over the age of 60. PD pathology is marked by intracellular inclusions composed primarily of the protein α-synuclein (α-syn). These inclusions also contain copper and the...

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Bibliografiske detaljer
Main Authors: Dudzik, Christopher G., Walter, Eric D., Millhauser, Glenn L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064431/
https://ncbi.nlm.nih.gov/pubmed/21319811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101912q
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