Deletion of Kaposi's Sarcoma-Associated Herpesvirus FLICE Inhibitory Protein, vFLIP, from the Viral Genome Compromises the Activation of STAT1-Responsive Cellular Genes and Spindle Cell Formation in Endothelial Cells

Kaposi's sarcoma herpesvirus (KSHV) Fas-associated death domain (FADD)-like interleukin-1 beta-converting enzyme (FLICE)-inhibitory protein, vFLIP, has antiapoptotic properties, is a potent activator of the NF-κB pathway, and induces the formation of endothelial spindle cells, the hallmark of K...

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Hlavní autoři: Alkharsah, Khaled R., Singh, Vivek Vikram, Bosco, Raffaella, Santag, Susann, Grundhoff, Adam, Konrad, Andreas, Stürzl, Michael, Wirth, Dagmar, Dittrich-Breiholz, Oliver, Kracht, Michael, Schulz, Thomas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196410/
https://ncbi.nlm.nih.gov/pubmed/21795355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00226-11
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