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Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in mice

Kaposi sarcoma herpesvirus (KSHV) is specifically associated with Kaposi sarcoma (KS) and 2 B cell lymphoproliferative diseases, namely primary effusion lymphoma (PEL) and multicentric Castleman disease (MCD). KS, PEL, and MCD are largely incurable and poorly understood diseases most common in HIV-i...

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Detalhes bibliográficos
Main Authors: Ballon, Gianna, Chen, Kang, Perez, Rocio, Tam, Wayne, Cesarman, Ethel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049379/
https://ncbi.nlm.nih.gov/pubmed/21339646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44417
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