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Kaposi's sarcoma associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a

Kaposi's sarcoma (KS) associated herpesvirus (KSHV)-encoded viral FLICE inhibitory protein (vFLIP) K13 is a potent activator of the NF-κB pathway. Here we demonstrate that infection with KHSV and ectopic expression of K13, but not its NF-κB-defective mutant, suppressed the expression of CXCR4....

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Detalhes bibliográficos
Main Authors: Punj, Vasu, Matta, Hittu, Schamus, Sandra, Tamewitz, Aletheia, Anyang, Bean, Chaudhary, Preet M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845732/
https://ncbi.nlm.nih.gov/pubmed/20023696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.460
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