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Activation of NF-κB by the Latent vFLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus Is Required for the Spindle Shape of Virus-Infected Endothelial Cells and Contributes to Their Proinflammatory Phenotype

Kaposi's sarcoma (KS) is an inflammatory angioproliferative lesion induced by the infection of endothelial cells with the KS-associated herpesvirus (KSHV). Infected endothelial cells assume an elongated (spindle) shape that is one of the histologic signatures of KS. In vitro, latent viral infec...

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Autors principals: Grossmann, Claudia, Podgrabinska, Simona, Skobe, Mihaela, Ganem, Don
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489050/
https://ncbi.nlm.nih.gov/pubmed/16809323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01603-05
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