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Anti-angiogenic agent sunitinib transiently increases tumor oxygenation and suppresses cycling hypoxia

Structural and functional abnormalities in tumor blood vessels impact the delivery of oxygen and nutrients to solid tumors, resulting chronic and cycling hypoxia. While chronically hypoxic regions exhibit treatment resistance, more recently it has been shown that cycling hypoxic regions acquire pro-...

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Detaylı Bibliyografya
Asıl Yazarlar: Matsumoto, Shingo, Batra, Sonny, Saito, Keita, Yasui, Hironobu, Choudhuri, Rajani, Gadisetti, Chandramouli, Subramanian, Sankaran, Devasahayam, Nallathamby, Munasinghe, Jeeva P., Mitchell, James B., Krishna, Murali C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196374/
https://ncbi.nlm.nih.gov/pubmed/21878530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2025
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