Longitudinal Imaging Studies of Tumor Microenvironment in Mice Treated with the mTOR Inhibitor Rapamycin

Rapamycin is an allosteric inhibitor of mammalian target of rapamycin, and inhibits tumor growth and angiogenesis. Recent studies suggested a possibility that rapamycin renormalizes aberrant tumor vasculature and improves tumor oxygenation. The longitudinal effects of rapamycin on angiogenesis and t...

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Detalhes bibliográficos
Main Authors: Saito, Keita, Matsumoto, Shingo, Yasui, Hironobu, Devasahayam, Nallathamby, Subramanian, Sankaran, Munasinghe, Jeeva P., Patel, Vyomesh, Gutkind, J. Silvio, Mitchell, James B., Krishna, Murali C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502528/
https://ncbi.nlm.nih.gov/pubmed/23185335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049456
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