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Anti-angiogenic agent sunitinib transiently increases tumor oxygenation and suppresses cycling hypoxia

Structural and functional abnormalities in tumor blood vessels impact the delivery of oxygen and nutrients to solid tumors, resulting chronic and cycling hypoxia. While chronically hypoxic regions exhibit treatment resistance, more recently it has been shown that cycling hypoxic regions acquire pro-...

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主要な著者: Matsumoto, Shingo, Batra, Sonny, Saito, Keita, Yasui, Hironobu, Choudhuri, Rajani, Gadisetti, Chandramouli, Subramanian, Sankaran, Devasahayam, Nallathamby, Munasinghe, Jeeva P., Mitchell, James B., Krishna, Murali C.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196374/
https://ncbi.nlm.nih.gov/pubmed/21878530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2025
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