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Activation Kinetics of RAF Protein in the Ternary Complex of RAF, RAS-GTP, and Kinase on the Plasma Membrane of Living Cells: SINGLE-MOLECULE IMAGING ANALYSIS

RAS is an important cell signaling molecule, regulating the activities of various effector proteins, including the kinase c-RAF (RAF). Despite the critical function of RAS signaling, the activation kinetics have not been analyzed experimentally in living cells for any of the RAS effectors. Here, we...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Hibino, Kayo, Shibata, Tatsuo, Yanagida, Toshio, Sako, Yasushi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196144/
https://ncbi.nlm.nih.gov/pubmed/21862573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.262675
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