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A RasGTP-Induced Conformational Change in C-RAF Is Essential for Accurate Molecular Recognition
The dysregulation of Ras-RAF signaling is associated with many types of human cancer. However, the kinetic and dynamic features of the mutual molecular recognition of Ras and RAF remain unknown. Here, we developed a technique for imaging single-pair fluorescence resonance energy transfer in living c...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325157/ https://ncbi.nlm.nih.gov/pubmed/19720015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.048 |
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