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Interaction of Nectin-like Molecule 2 with Integrin α(6)β(4) and Inhibition of Disassembly of Integrin α(6)β(4) from Hemidesmosomes

In normal epithelial cells, integrin α(6)β(4) is abundantly expressed and forms hemidesmosomes, which is a cellular structure that mediates cell-extracellular matrix binding. In many types of cancer cells, integrin α(6)β(4) is up-regulated, laminin is cleaved, and hemidesmosomes are disrupted, event...

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Main Authors: Mizutani, Kiyohito, Kawano, Satoshi, Minami, Akihiro, Waseda, Masazumi, Ikeda, Wataru, Takai, Yoshimi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196104/
https://ncbi.nlm.nih.gov/pubmed/21880726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200535
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