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Reduction of the ST6 β-Galactosamide α-2,6-Sialyltransferase 1 (ST6GAL1)-catalyzed Sialylation of Nectin-like Molecule 2/Cell Adhesion Molecule 1 and Enhancement of ErbB2/ErbB3 Signaling by MicroRNA-199a

Nectin-like molecule 2 (Necl-2)/cell adhesion molecule 1 (CADM1) is shown to be down-regulated by the promoter hypermethylation and/or loss of heterozygosity at chromosome 11q23.2 in many types of cancers, including lung and breast cancers, and is proposed to serve as a tumor suppressor. However, th...

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Bibliografske podrobnosti
Main Authors: Minami, Akihiro, Shimono, Yohei, Mizutani, Kiyohito, Nobutani, Kentaro, Momose, Kenji, Azuma, Takeshi, Takai, Yoshimi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636872/
https://ncbi.nlm.nih.gov/pubmed/23504322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.405993
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