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Interaction of Nectin-like Molecule 2 with Integrin α(6)β(4) and Inhibition of Disassembly of Integrin α(6)β(4) from Hemidesmosomes
In normal epithelial cells, integrin α(6)β(4) is abundantly expressed and forms hemidesmosomes, which is a cellular structure that mediates cell-extracellular matrix binding. In many types of cancer cells, integrin α(6)β(4) is up-regulated, laminin is cleaved, and hemidesmosomes are disrupted, event...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196104/ https://ncbi.nlm.nih.gov/pubmed/21880726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200535 |
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