Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface

Apart from its role in insulin receptor (IR) activation, the C terminus of the B-chain of insulin is also responsible for the formation of insulin dimers. The dimerization of insulin plays an important role in the endogenous delivery of the hormone and in the administration of insulin to patients. H...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Antolíková, Emília, Žáková, Lenka, Turkenburg, Johan P., Watson, Christopher J., Hančlová, Ivona, Šanda, Miloslav, Cooper, Alan, Kraus, Tomáš, Brzozowski, A. Marek, Jiráček, Jiří
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196076/
https://ncbi.nlm.nih.gov/pubmed/21880708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.265249
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky