Mammalian Testis-determining Factor SRY and the Enigma of Inherited Human Sex Reversal: FRUSTRATED INDUCED FIT IN A BENT PROTEIN-DNA COMPLEX

Mammalian testis-determining factor SRY contains a high mobility group box, a conserved eukaryotic motif of DNA bending. Mutations in SRY cause XY gonadal dysgenesis and somatic sex reversal. Although such mutations usually arise de novo in spermatogenesis, some are inherited and so specify male dev...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Phillips, Nelson B., Racca, Joseph, Chen, Yen-Shan, Singh, Rupinder, Jancso-Radek, Agnes, Radek, James T., Wickramasinghe, Nalinda P., Haas, Elisha, Weiss, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196072/
https://ncbi.nlm.nih.gov/pubmed/21849498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260091
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados