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Switching on sex: transcriptional regulation of the testis-determining gene Sry

Mammalian sex determination hinges on the development of ovaries or testes, with testis fate being triggered by the expression of the transcription factor sex-determining region Y (Sry). Reduced or delayed Sry expression impairs testis development, highlighting the importance of its accurate spatiot...

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Autors principals: Larney, Christian, Bailey, Timothy L., Koopman, Peter
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034426/
https://ncbi.nlm.nih.gov/pubmed/24866114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.107052
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