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Role of Amino-terminal Half of the S4-S5 Linker in Type 1 Ryanodine Receptor (RyR1) Channel Gating

The type 1 ryanodine receptor (RyR1) is a Ca(2+) release channel found in the sarcoplasmic reticulum of skeletal muscle and plays a pivotal role in excitation-contraction coupling. The RyR1 channel is activated by a conformational change of the dihydropyridine receptor upon depolarization of the tra...

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Autors principals: Murayama, Takashi, Kurebayashi, Nagomi, Oba, Toshiharu, Oyamada, Hideto, Oguchi, Katsuji, Sakurai, Takashi, Ogawa, Yasuo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195593/
https://ncbi.nlm.nih.gov/pubmed/21862589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255240
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