High Cell Surface Death Receptor Expression Determines Type I Versus Type II Signaling

Previous studies have suggested that there are two signaling pathways leading from ligation of the Fas receptor to induction of apoptosis. Type I signaling involves Fas ligand-induced recruitment of large amounts of FADD (FAS-associated death domain protein) and procaspase 8, leading to direct activ...

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Hlavní autoři: Meng, Xue Wei, Peterson, Kevin L., Dai, Haiming, Schneider, Paula, Lee, Sun-Hee, Zhang, Jin-San, Koenig, Alexander, Bronk, Steve, Billadeau, Daniel D., Gores, Gregory J., Kaufmann, Scott H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195573/
https://ncbi.nlm.nih.gov/pubmed/21865165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.240432
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