Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Disease outcome has been related to the severity of the proinflammatory response in the subarachnoid space. The complement sy...

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Detalhes bibliográficos
Main Authors: Woehrl, Bianca, Brouwer, Matthijs C., Murr, Carmen, Heckenberg, Sebastiaan G.B., Baas, Frank, Pfister, Hans W., Zwinderman, Aeilko H., Morgan, B. Paul, Barnum, Scott R., van der Ende, Arie, Koedel, Uwe, van de Beek, Diederik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195471/
https://ncbi.nlm.nih.gov/pubmed/21926466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57522
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