Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Early recognition of the pathogen and subsequent innate immune response play a vital role in disease susceptibility and outcome. Genetic variations in innate immune genes can alter the immune response and influence s...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Ferwerda, Bart, Valls Serón, Mercedes, Jongejan, Aldo, Zwinderman, Aeilko H., Geldhoff, Madelijn, van der Ende, Arie, Baas, Frank, Brouwer, Matthijs C., van de Beek, Diederik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006661/
https://ncbi.nlm.nih.gov/pubmed/27432718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.07.011
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