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Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Early recognition of the pathogen and subsequent innate immune response play a vital role in disease susceptibility and outcome. Genetic variations in innate immune genes can alter the immune response and influence s...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Ferwerda, Bart, Valls Serón, Mercedes, Jongejan, Aldo, Zwinderman, Aeilko H., Geldhoff, Madelijn, van der Ende, Arie, Baas, Frank, Brouwer, Matthijs C., van de Beek, Diederik
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006661/
https://ncbi.nlm.nih.gov/pubmed/27432718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.07.011
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