Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Disease outcome has been related to the severity of the pro-inflammatory response in the subarachnoid space. The...

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發表在:J Neuroinflammation
Main Authors: Kasanmoentalib, E. Soemirien, Valls Seron, Mercedes, Ferwerda, Bart, Tanck, Michael W., Zwinderman, Aeilko H., Baas, Frank, van der Ende, Arie, Brouwer, Matthijs C., van de Beek, Diederik
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234106/
https://ncbi.nlm.nih.gov/pubmed/28086930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0770-9
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