Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial

BACKGROUND: We compared adjunctive treatment with placebo, dexamethasone, anti-C5 antibodies, and the combination of dexamethasone plus anti-C5 antibodies in experimental pneumococcal meningitis. METHODS: In this prospective, investigator-blinded, randomized trial, 96 mice were infected intracistern...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Kasanmoentalib, E. Soemirien, Valls Seron, Mercedes, Morgan, B. Paul, Brouwer, Matthijs C., van de Beek, Diederik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536776/
https://ncbi.nlm.nih.gov/pubmed/26272468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0372-y
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