Genetic Variation in the β2-Adrenocepter Gene Is Associated with Susceptibility to Bacterial Meningitis in Adults

Recently, the biased β2-adrenoceptor/β-arrestin pathway was shown to play a pivotal role in crossing of the blood brain barrier by Neisseria meningitidis. We hypothesized that genetic variation in the β2-adrenoceptor gene (ADRB2) may influence susceptibility to bacterial meningitis. In a prospective...

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Bibliografiske detaljer
Main Authors: Adriani, Kirsten S., Brouwer, Matthijs C., Baas, Frank, Zwinderman, Aeilko H., van der Ende, Arie, van de Beek, Diederik
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356289/
https://ncbi.nlm.nih.gov/pubmed/22624056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037618
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