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Hepatocyte IKK2 Protects Mdr2(−/−) Mice from Chronic Liver Failure
Mice lacking the Abc4 protein encoded by the multidrug resistance-2 gene (Mdr2 (−/−)) develop chronic periductular inflammation and cholestatic liver disease resulting in the development of hepatocellular carcinoma (HCC). Inhibition of NF-κB by expression of an IκBα super-repressor (IκBαSR) transgen...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3195080/ https://ncbi.nlm.nih.gov/pubmed/22022477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025942 |
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