Increased pfmdr1 Copy Number and Sequence Polymorphisms in Plasmodium falciparum Isolates from Sudanese Malaria Patients Treated with Artemether-Lumefantrine

Molecular markers for surveillance of Plasmodium falciparum resistance to current antimalarials are sorely needed. A 28-day efficacy study of artemether-lumefantrine in eastern Sudan identified 5 treatment failures among 100 evaluable patients; 9 further individuals were parasite positive by PCR dur...

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Detalhes bibliográficos
Main Authors: Gadalla, Nahla B., Adam, Ishag, Elzaki, Salah-Eldin, Bashir, Sahar, Mukhtar, Izdihar, Oguike, Mary, Gadalla, Amal, Mansour, Fathi, Warhurst, David, El-Sayed, Badria B., Sutherland, Colin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195064/
https://ncbi.nlm.nih.gov/pubmed/21896916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05102-11
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