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Prolonged Selection of pfmdr1 Polymorphisms After Treatment of Falciparum Malaria With Artemether-Lumefantrine in Uganda

We compared the prevalence of key pfmdr1 alleles between pretreatment Plasmodium falciparum parasite isolates and parasites that emerged after treatment of uncomplicated malaria in a longitudinal cohort of Ugandan children. The pfmdr1 86N, 184F, and 1246D alleles were selected after treatment with a...

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Detalhes bibliográficos
Main Authors: Baliraine, Frederick N., Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164433/
https://ncbi.nlm.nih.gov/pubmed/21881128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir486
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