Biochemical Characterization of Sfh-I, a Subclass B2 Metallo-β-Lactamase from Serratia fonticola UTAD54

The subclass B2 metallo-β-lactamase (MBL) Sfh-I from Serratia fonticola UTAD54 was cloned and overexpressed in Escherichia coli. The recombinant protein binds one equivalent of zinc, as shown by mass spectrometry, and preferentially hydrolyzes carbapenem substrates. However, compared to other B2 MBL...

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Detaylı Bibliyografya
Asıl Yazarlar: Fonseca, Fátima, Arthur, Christopher J., Bromley, Elizabeth H. C., Samyn, Bart, Moerman, Pablo, Saavedra, Maria José, Correia, António, Spencer, James
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195014/
https://ncbi.nlm.nih.gov/pubmed/21876065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00429-11
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